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(hide this warning on this page)The IU Vector Production Facility (VPF) is a core laboratory within the Cell & Gene Therapy Manufacturing facility at Indiana University School of Medicine that is dedicated to the production of gene therapy products (lentiviruses and retroviruses). The VPF produces both GMP-grade and non-clinical grade vectors that are certified by the IU Gene Therapy Testing Lab (GTTL - testing services can be found on the IU GTTL page).
| Service/Production Category | Service/Production Title | FY 2025 | |
| IU Internal Pricing | |||
| *RQ= Request Quote | |||
| VECTOR PRODUCTIONS | |||
| "GMP" Vector Production | MCB/WMCB (100 vial) | RQ | |
| MCB/WMCB (200 vial) | RQ | ||
| MCB/WMCB (400 vial) | RQ | ||
| Clone selection | RQ | ||
| 10L(10x1) GMP Lenti | RQ | ||
| 10L(5x2) GMP Lenti | RQ | ||
| 20L (20x1) GMP Lenti | RQ | ||
| 20L (10x2) GMP Lenti | RQ | ||
| 30L (30x1) GMP Lenti | $309,767.31 | ||
| 40L (20x2) GMP Lenti | RQ | ||
| 60L (30x2) GMP Lenti | RQ | ||
| 9L GMP Retro (50g) | RQ | ||
| 9L GMP Retro (100g) | RQ | ||
| GMP Comparable Production | 10L (10x1) COMP/cGMP Lenti | RQ | |
| 10L (5x2) COMP/cGMP Lenti | RQ | ||
| 20L (20x1) COMP/cGMP Leni | RQ | ||
| 20L (10x2) COMP/cGMP Lenti | RQ | ||
| MISC/ADD-ON SERVICES/ITEMS | |||
| GMP Facility Compliance Fees | NGVB Freezer Annual Fee | $4,216.67 | |
| NGVB Dewar Annual Fee | $4,216.67 | ||
| Gowned Entry (1 person) - per access | $638.22 | ||
| Time & Temp Study | RQ | ||
| Custom Transgene Plasmids | Production & Sequencing (w/o Supplies) | RQ | |
| Addn'l Prep Fee ($/hour) | RQ | ||
| VPF Packaging Plasmids | for ≤10L Production | RQ | |
| for 20 or 40L Produciton | RQ | ||
| for 30 or 60L Produciton | $6,394.56 | ||
| Media Addition (per 1 L) | OptiPRO (1 L) Media (w/ Phenol Red) | RQ | |
| OptiPRO (1 L) Refeed Media (Phenol free) | RQ | ||
| TEXMACS (1L) Media | RQ | ||
| XVIVO 10 (1L) Media | RQ | ||
| X VIVO 15 (1L) Media | RQ | ||
| GMP SCGM (1L) Media | RQ | ||
| RPMI (1L) Media | $50.37 | ||
| Additional Staff Time (per Hour) | Sr. Lab Tech/Lab Leader/Management | RQ | |
| Lab Tech/Technologist | $719.23 | ||
| Emily Hopewell |
| Director of Cell & Gene Therapy Manufacturing |
| Hours | Location |
|
Monday-Friday 8:00 am-5:00 pm |
Building R3-C602 980 West Walnut Street Indianapolis, IN 46202 |
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Daniela Bischof, PhD |
Director of Vector Production
|
317-278-6518
|
dabischo@iu.edu
|
IUPUI Campus, R3-602
|
| Emily Hopewell |
Director of Cell & Gene Therapy Manufacturing
|
317-278-1109
|
emlhope@iu.edu
|
IUPUI Campus, R3-602
|
| Service list |
| ► GMP (9) | |||
| Name | Description | Price | |
|---|---|---|---|
| 10L(10X1) GMP Lenti - Request Quote |
GMP Production of a 10L Lentiviral Vector (10L x 1 harvest) includes: Supplies, Labor and Cleanroom Facility fee. |
Inquire | |
| 10L(5X2) GMP Lenti - Request Quote |
|
Inquire | |
| 20L (10X2) GMP Lenti - Request Quote |
GMP Production of a 20L Lentiviral Vector (10L x 2 harvests) includes: Supplies, Labor and Cleanroom Facility fee. |
Inquire | |
| 20L (20X1) GMP Lenti - Request Quote |
GMP Production of a 20L Lentiviral Vector (20L x 1 harvest) includes: Supplies, Labor and Cleanroom Facility fee. |
Inquire | |
| 30L (30X1) GMP Lenti |
GMP Production of a 30L Lentiviral Vector (30L x 1 harvests) includes: Supplies, Labor and Cleanroom Facility fee. |
Inquire | |
| 40L (20X2) GMP Lenti - Request Quote |
GMP Production of a 40L Lentiviral Vector (20L x 2 harvests) includes: Supplies, Labor and Cleanroom Facility fee. |
Inquire | |
| 60L (30X2) GMP Lenti - Request Quote |
GMP Production of a 60L Lentiviral Vector (30L x 2 harvests) includes: Supplies, Labor and Cleanroom Facility fee. |
Inquire | |
| 9L Retro (50 or 100g) - Request Quote |
GMP Production of a 50g or 100g 9L Standard Retroviral Vector includes: Supplies, Labor and Cleanroom Facility fee. |
Inquire | |
| MCB (100, 200 or 400 vials) - Request Quote |
GMP Production of a 100, 200 or 400 vial Master Cell Bank - includes: Supplies, Labor and Cleanroom Facility fee |
Inquire | |
| ► Non-GMP (3) | |||
| Name | Description | Price | |
| 10L (10X1) non-GMP Lenti -Request Qupte |
Non-GMP Production of a 10L Lentiviral Vector (10L x 1 harvest) includes: Supplies, Labor and Cleanroom Facility fee. |
Inquire | |
| 10L (5X2) non-GMP Lenti - Request Quote |
Non-GMP Production of a 10L Lentiviral Vector (5L x 2 harvests) includes: Supplies, Labor and Cleanroom Facility fee. |
Inquire | |
| 20L (10X2) non-GMP Lenti - Request Quote |
Non-GMP Production of a 20L Lentiviral Vector (10L x 2 harvests) includes: Supplies, Labor and Cleanroom Facility fee. |
Inquire | |
